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KMID : 0358419970400030645
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Korean Journal of Obstetrics and Gynecology
1997 Volume.40 No. 3 p.645 ~ p.651
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A Case of Cyclopia Delivered from a Diabetic Mother
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Abstract
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Cyclopia is a rare congenital fetal anomaly, characterized by a single median eye and a grotesquely shaped nose(proboscis) that arises from the supraorbital area. It is consistently associated with severe holoprosencephaly, which is the failure
of
cleavage of the prosencephalon with a deficite in the midline facial development. Holoprosencephaly occurs in as many as 1 to 2% of diabetic mothers. A case of cyclopia delivered from a diabetic mother is presented with a brief review of
literatures.
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